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Invitrogen™ DUSP14 Polyclonal Antibody
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Catalog No. PIPA5120080
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100 μL
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PIPA5120080 100 μL
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Catalog No. PIPA5120080 Supplier Invitrogen™ Supplier No. PA5120080
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Description

Rabbit Polyclonal Antibody

Positive test controls include: Hela, SW480, BT-474, SKOV3, Mouse kidney, Mouse brain. Immunogen sequence: MSSRGHSTLP RTLMAPRMIS EGDIGGIAQI TSSLFLGRGS VASNRHLLQA RGITCIVNAT IEIPNFNWPQ FEYVKVPLAD MPHAPIGLYF DTVADKIHSV SRKHGATLVH CAAGVSRSAT LCIAYLMKFH NVCLLEAYNW VKARRPVIRP NVGFWRQLID YERQLFGKST VKMVQTPYGI VPDVYEKESR HLMPYWGI.

In addition to antigen recognition by the T-cell receptor, T-cell activation requires a second signal from a costimulatory receptor, such as CD28 (MIM 186760), which interacts with B7-1 (CD80; MIM 112203) and B7-2 (CD86; MIM 601020) ligands on antigen-presenting cells. CD28 costimulation induces transcription of interleukin-2 (IL2; MIM 147680) and stabilizes newly synthesized IL2 through the activation of mitogen-activated protein kinases (MAPKs), such as ERK (e.g., MAP2K4; MIM 601335) and JNK (see MIM 601158), and the subsequent creation of AP1 transcription factor (see MIM 165160). DUSP14 is a negative regulator of CD28 signaling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DUSP14
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.11 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene DUSP14
Gene Accession No. O95147, Q9JLY7
Gene Alias 1110014C10Rik; 2310042C07Rik; D11Ertd395e; dual specificity phosphatase 14; dual specificity protein phosphatase 14; DUSP14; MAP kinase phosphatase 6; MAP kinase phsophatase 6; mitogen-activated protein kinase phosphatase 6; Mkp-1 like protein tyrosine phosphatase; MKP-1-like protein tyrosine phosphatase; MKP6; MKP-6; MKP-L
Gene Symbols DUSP14
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human DUSP14 (NP_008957.1).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11072, 360580, 56405
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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