Invitrogen™ DUSP16 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587683

Catalog No. PIPA587683

Description

Immunogen sequence: SLHGFSSSED ALEYYKPSTT LDGTNKLCQF SPVQELSEQT PETSPDKEEA SIPKKLQTAR PSDSQSKRLH SVRTSSSGTA QRSLLSPLHR SGSVEDNYHT SFLFGLSTSQ QHLTKSAGLG LKGWHSDILA PQTSTPSLTS SWYFATESSH FYSASAIYGG SASYSAYSCS QLPTCGDQVY SVRRRQKPSD RADSRRSWHE ESPFEKQFKR RSCQMEFGES IMSENRSREE LGKVGSQSSF SGSMEIIEVS; Positive Samples: HeLa, A-549, K-562, HepG2, Mouse liver; Cellular Location: Cytoplasm, Cytoplasmic vesicle, Nucleus.

Dual-specificity phosphatases constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP16 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK proteins ERK, JNK, and p38 with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25-like domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses.

Specifications

• Antigen: DUSP16
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DUSP16
• Gene Alias: 3830417M17Rik; AW558566; D6Ertd213e; dual specificity phosphatase 16; dual specificity protein phosphatase 16; Dusp16; KIAA1700; MAP kinase phosphatase 7; MAP kinase phosphatase-7; map kinase phosphatase-M; MAPK phosphatase-7; MGC129701; MGC129702; mitogen-activated protein kinase phosphatase 7; Mkp7; MKP-7; Mkpm
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 297682, 70686, 80824
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.33 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9BY84
• Gene Symbols: DUSP16
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 416-665 of human DUSP16 (NP_0851431).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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