Invitrogen™ DUSP22 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA533487

Catalog No. PIPA533487

Description

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Bovine, Horse, Rabbit (100%) Mouse, Rat (94%) Elephant, Chicken (88%) Xenopus (82%).

Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.

Specifications

• Antigen: DUSP22
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Dusp22
• Gene Alias: DKFZp586F2224; dual specificity phosphatase 22; dual specificity protein phosphatase 22; Dusp22; homolog of mouse dual specificity phosphatase LMW-DSP2; JKAP; JNK-stimulating phosphatase 1; JNK-stimulatory phosphatase-1; JSP 1; JSP1; JSP-1; LMWDSP2; LMW-DSP2; low molecular weight dual specificity phosphatase 2; MAP kinase phosphatase x; mi; mitogen-activated protein kinase phosphatase x; MKPX; MKP-x; PYST2; VHX
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100054792, 100353877, 56940, 787471
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q9NRW4
• Gene Symbols: Dusp22
• Immunogen: Synthetic 17 amino acid peptide from near N-terminus of human DUSP22.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Rabbit, Monkey, Bovine, Horse
• Product Type: Antibody
• Isotype: IgG