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Invitrogen™ DUSP22 Polyclonal Antibody
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Catalog No. PIPA533489
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50 μg
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PIPA533489 50 μg
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Catalog No. PIPA533489 Supplier Invitrogen™ Supplier No. PA533489
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Bovine, Horse, Rabbit (100%) Mouse, Rat, Panda, Turkey, Chicken (94%).

Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DUSP22
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene Dusp22
Gene Accession No. Q9NRW4
Gene Alias DKFZp586F2224; dual specificity phosphatase 22; dual specificity protein phosphatase 22; Dusp22; homolog of mouse dual specificity phosphatase LMW-DSP2; JKAP; JNK-stimulating phosphatase 1; JNK-stimulatory phosphatase-1; JSP 1; JSP1; JSP-1; LMWDSP2; LMW-DSP2; low molecular weight dual specificity phosphatase 2; MAP kinase phosphatase x; mi; mitogen-activated protein kinase phosphatase x; MKPX; MKP-x; PYST2; VHX
Gene Symbols Dusp22
Host Species Rabbit
Immunogen Synthetic 17 amino acid peptide from internal region of human DUSP22.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100054792, 100353877, 56940, 787471
Target Species Human, Rabbit, Monkey, Bovine, Horse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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