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Invitrogen™ DUSP22 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA550221
Description
The antibody detects endogenous levels of total DUSP22 / JSP1 protein.
Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.
Specifications
DUSP22 | |
Polyclonal | |
Unconjugated | |
Dusp22 | |
DKFZp586F2224; dual specificity phosphatase 22; dual specificity protein phosphatase 22; Dusp22; homolog of mouse dual specificity phosphatase LMW-DSP2; JKAP; JNK-stimulating phosphatase 1; JNK-stimulatory phosphatase-1; JSP 1; JSP1; JSP-1; LMWDSP2; LMW-DSP2; low molecular weight dual specificity phosphatase 2; MAP kinase phosphatase x; mi; mitogen-activated protein kinase phosphatase x; MKPX; MKP-x; PYST2; VHX | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
56940 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin) | |
3 mg/mL | |
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4 | |
Q9NRW4 | |
Dusp22 | |
Full length fusion protein of Human DUSP22. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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