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Invitrogen™ DUSP22 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550221

Catalog No. PA550221


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Description

Description

The antibody detects endogenous levels of total DUSP22 / JSP1 protein.

Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

DUSP22
Polyclonal
Unconjugated
Dusp22
DKFZp586F2224; dual specificity phosphatase 22; dual specificity protein phosphatase 22; Dusp22; homolog of mouse dual specificity phosphatase LMW-DSP2; JKAP; JNK-stimulating phosphatase 1; JNK-stimulatory phosphatase-1; JSP 1; JSP1; JSP-1; LMWDSP2; LMW-DSP2; low molecular weight dual specificity phosphatase 2; MAP kinase phosphatase x; mi; mitogen-activated protein kinase phosphatase x; MKPX; MKP-x; PYST2; VHX
Rabbit
Antigen affinity chromatography
RUO
56940
-20°C
Liquid
Immunohistochemistry (Paraffin)
3 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Q9NRW4
Dusp22
Full length fusion protein of Human DUSP22.
100 μL
Primary
Human
Antibody
IgG
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