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DUSP22 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987705
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50-198-7705 100 μL
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Catalog No. 50-198-7705 Supplier Bioss Supplier No. BS7066R
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Description

Rabbit Polyclonal Antibody

Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.

Specifications

Antigen DUSP22
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Dusp22
Gene Accession No. Q9NRW4
Gene Alias DKFZp586F2224; dual specificity phosphatase 22; Dual specificity protein phosphatase 22; DUSP22; homolog of mouse dual specificity phosphatase LMW-DSP2; JKAP; JNK-stimulating phosphatase 1; JNK-stimulatory phosphatase-1; JSP 1; JSP1; JSP-1; LMWDSP2; LMW-DSP2; Low molecular weight dual specificity phosphatase 2; MAP kinase phosphatase x; mi; Mitogen-activated protein kinase phosphatase x; MKPX; MKP-x; PYST2; VHX
Gene Symbols Dusp22
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human DUSP22/JSP1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56940
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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