DUSP6 Rabbit anti-Human, Clone: 9C3 , Bioss

Rabbit Monoclonal Antibody

Supplier:  Bioss BSM52270R

Catalog No. 50-198-9667

Description

DUSP6 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP)kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associatedwith cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Twotranscript variants encoding different isoforms have been found for the DUSP6 gene.

Specifications

• Antigen: DUSP6
• Classification: Monoclonal
• Concentration: 1 μg/mL
• Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
• Gene Accession No.: Q16828
• Gene Symbols: DUSP6
• Immunogen: Recombinant protein within Human DUSP6 aa 1-350.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: 9C3
• Conjugate: Unconjugated
• Gene: DUSP6
• Gene Alias: 1300019I03Rik; dual specificity phosphatase 6; Dual specificity protein phosphatase 6; Dual specificity protein phosphatase PYST1; DUSP6; DUSP6-ALT; HH19; MAP kinase phosphatase 3; Mitogen-activated protein kinase phosphatase 3; Mkp3; MKP-3; PYST1; serine/threonine specific protein phosphatase
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1848
• Content And Storage: -20°C
• Form: Liquid