Invitrogen™ DUSP7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA522014

Catalog No. PIPA522014

Description

Recommended positive controls: 293T, H1299, HepG2, Molt-4, Raji. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

DUSP7 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP)kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associatedwith cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.

Specifications

• Antigen: DUSP7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DUSP7
• Gene Alias: AU015694; dual specificity phosphatase 6; dual specificity phosphatase 7; dual specificity protein phosphatase 7; Dual specificity protein phosphatase MKP-X; dual specificity protein phosphatase PYST2; dual-specificity phosphatase-7; DUSP7; fd19d04; hypothetical protein LOC327246; MAP kinase phosphatase; Mkpx; mkp-X; PYST2; wu:fd19d04; zgc:55957; zgc:77211; zgc:77211 protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1849
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q16829
• Gene Symbols: DUSP7
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human DUSP7. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov