Invitrogen™ DVL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA540485

Catalog No. PIPA540485

Description

Peptide sequence: LKITIANAVI GADVVDWLYT HVEGFKERRE ARKYASSLLK HGFLRHTVNK Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 87%.

DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cellproliferation, acting as a transducer molecule for developmentalprocesses, including segmentation and neuroblast specification.DVL1 is a candidate gene for neuroblastomatous transformation. TheSchwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2Ahave been mapped to the same region as DVL1. The phenotypes ofthese diseases may be consistent with defects which might beexpected from aberrant expression of a DVL gene during development.

Specifications

• Antigen: DVL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DVL1
• Gene Alias: dishevelled 1; dishevelled 1 (homologous to Drosophila dsh); dishevelled segment polarity protein 1; dishevelled, dsh homolog 1; dishevelled, dsh homolog 1 (Drosophila); dishevelled-1; Dishevelled-1-like; DRS2; DSH homolog 1; DSH homolog 1-like; Dvl; Dvl1; dvl-1; DVL1L1; DVL1P1; MGC54245; mKIAA4029; RP5-890O3.5; segment polarity protein dishevelled homolog DVL-1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1855
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O14640
• Gene Symbols: DVL1
• Immunogen: Synthetic peptide directed towards the middle region of human DVL1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov