Invitrogen™ DVL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA540486

Catalog No. PIPA540486

Description

Peptide sequence: AGSSTGGGGV GETKVIYHLD EEETPYLVKI PVPAERITLG DFKSVLQRPA Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 82%; Zebrafish: 93%.

Disheveled DVL2 is a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.

Specifications

• Antigen: DVL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DVL2
• Gene Alias: dishevelled 2; dishevelled 2 (homologous to Drosophila dsh); dishevelled 2, dsh homolog; dishevelled 2, dsh homolog (Drosophila); dishevelled segment polarity protein 2; dishevelled, dsh homolog 2; dishevelled-2; DSH homolog 2; Dvl2; Dvl-2; LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-2; sb:eu471; Segment polarity protein dishevelled homolog DVL-2; wu:fc05d12; wu:fo71e09; wu:fp54a02; zgc:55372
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1856
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O14641
• Gene Symbols: DVL2
• Immunogen: Synthetic peptide directed towards the N-terminal of human DVL2 (aa 2-51).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov