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Invitrogen™ Dynactin 2 Polyclonal Antibody
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Catalog No. PIPA583486
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PIPA583486 100 μL
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Catalog No. PIPA583486 Supplier Invitrogen™ Supplier No. PA583486
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RWSPIASTLP ELVQRLVTIK QLHEQAMQFG QLLTHLDTTQ QMIANSLKDN TTLLTQVQTT MRENLATVEG NFASIDERMK KL Highest antigen sequence indentity to the following orthologs: Rat - 94%, Mouse - 93%.

This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kDa. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Dynactin 2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene DCTN2
Gene Accession No. Q13561, Q6AYH5, Q99KJ8
Gene Alias 2310042E05Rik; 50 kDa dynein-associated polypeptide; C130077D06Rik; C87049; DCTN2; dctn2 protein; DCTN50; DCTN-50; dynactin 2; dynactin 2 (p50); dynactin complex 50 kDa subunit; Dynactin subunit 2; dynamitin; epididymis secretory protein Li 77; GMP23-48K; Growth cone membrane protein 23-48K; HEL-S-77; hypothetical protein LOC527201; p50; p50 dynamitin; p50/dynamitin; RBP50; zgc:63867
Gene Symbols DCTN2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human DCTN2. Recombinant protein control fragment (Product #RP-97824).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10540, 299850, 69654
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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