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Invitrogen™ Dynactin 3 Polyclonal Antibody
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Catalog No. PIPA530437
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100 μL
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PIPA530437 100 μL
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Catalog No. PIPA530437 Supplier Invitrogen™ Supplier No. PA530437
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A549, HeLa, HepG2, HCT116. Predicted reactivity: Mouse (81%), Rat (81%), Rhesus Monkey (84%), Bovine (80%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Dynactin 3
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene DCTN3
Gene Accession No. O75935
Gene Alias DCTN22; DCTN-22; DCTN3; dynactin 3; dynactin 3 (p22); dynactin complex subunit 22 kDa subunit; dynactin light chain; dynactin light chain (P24); dynactin light chain p24; Dynactin subunit 3; MGC111190; p22; p24; p24 dynactin light chain
Gene Symbols DCTN3
Host Species Rabbit
Immunogen Full length human DCTN3 Recombinant protein.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11258
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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