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Invitrogen™ Dynamin 1 Polyclonal Antibody

Rabbit Polyclonal Antibody

$209.50 - $511.50

Specifications

Antigen Dynamin 1
Concentration 500 μg/mL
Content And Storage -20°C
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
PIPA5119089
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Invitrogen™
PA5119089
200 μL
Each for $511.50
Only null left
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PIPA5122022
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Invitrogen™
PA5122022
20 μL
Each for $209.50
Only null left
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Description

Description

Dynamin 1 Polyclonal Antibody for Western Blot, IHC (P)

Dynamin is a GTPase required for endocytosis of clathrin coated vesicles from the membrane. Dynamin's involvement in endocytosis was first discovered during the characterization of the temperature sensitive parylytic shibire mutation from Drosophila melanogaster. Three closely related isoforms have been identified in mammals. Dynamin1 is expressed exclusively in neurons, dynamin2 is ubiquitously expressed and dynamin3 is expressed primarily in the testes. Each of these isoforms of dynamin also has several splice variants. This suggests that each isoform/splice variant may have separate intracellular targets or function in the budding of distinct vesicle types. Common domain features of the dynamin proteins include an amino acid terminal GTPase domain, a central pleckstrin homology domain and a highly basic proline rich carboxyl terminus with several Src homology 3 (SH3) domains. These SH3 domains target the dynamin to the clathrin coated pit. Dynamin is known to interact with at least two proteins, AP2 adaptor protein complex and amphiphysin.
Specifications

Specifications

Dynamin 1
-20°C
Polyclonal
Liquid
IgG
Mouse
DNM1
AI838169; B-dynamin; D100; Dnm; Dnm1; Dyn1; dynamin 1; Dynamin BREDNM19; dynamin i; dynamin, brain; Dynamin1; Dynamin-1; EC 3.6.5.5; EIEE31; Ftfl; Kiaa4093; mKIAA4093; Neuronal dynamin; OTTHUMP00000215500
DNM1
Primary
Antigen Affinity Chromatography
500 μg/mL
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Rabbit
RUO
PBS with 50% glycerol and 0.05% ProClin 300
P39053
13429
Recombinant protein Dynamin 1. The antigen corresponds to amino acid range 572-745 of the target protein.
Antibody
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