Invitrogen™ Dynamin 2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529658

Catalog No. PIPA529658

Description

Recommended positive controls: A549, HeLa, mouse brain, PC-12, Rat-2, rat brain. Predicted reactivity: Mouse (99%), Rat (98%), Xenopus laevis (90%), Rhesus Monkey (100%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.

Specifications

• Antigen: Dynamin 2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DNM2
• Gene Alias: b2b2159Clo; CMT2M; CMTDI1; CMTDIB; DI-CMTB; Dnm2; DYIIAAB; Dyn2; dynamin 2; dynamin II; Dynamin UDNM; Dynamin-2; DYNII; LCCS5; Udnm
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13430, 1785, 25751
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.06 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P39052, P39054, P50570
• Gene Symbols: DNM2
• Immunogen: Recombinant fragment corresponding to a region within amino acids 100 and 334 of Human Dynamin 2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov