Invitrogen™ Dynamin 2 Recombinant Rabbit Monoclonal Antibody (JM61-38)

Catalog No.	Quantity
PIMA532729	100 μL

Catalog No. PIMA532729 Supplier Invitrogen™ Supplier No. MA532729

Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.

Specifications

• Antigen: Dynamin 2
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
• Classification: Recombinant Monoclonal
• Clone: JM61-38
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
• Gene: DNM2
• Gene Accession No.: P50570
• Gene Alias: b2b2159Clo; CMT2M; CMTDI1; CMTDIB; DI-CMTB; Dnm2; DYIIAAB; Dyn2; dynamin 2; dynamin II; Dynamin UDNM; Dynamin-2; DYNII; LCCS5; Udnm
• Gene Symbols: DNM2
• Host Species: Rabbit
• Immunogen: Synthetic peptide within Human Dynamin 2 aa 748-797.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1785
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG