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Invitrogen™ Dynamin 3 Polyclonal Antibody
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Catalog No. PA1662
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100 μL
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PA1662 100 μL
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Catalog No. PA1662 Supplier Invitrogen™ Supplier No. PA1662
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Description

Rabbit Polyclonal Antibody

PA1-662 detects dynamin III (Dyn3) from rat, mouse, and human tissues and cells. PA1-662 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~100 kDa protein representing Dyn3 from HeLa cell lysate. PA1-662 immunizing peptide corresponds to amino acid residues 623-639 from rat Dyn3. PA1-662 immunizing peptide (Cat. # PEP-057) is available for use in neutralization and control experiments.

The dynamins are a family of 100 kDa GTPases transcribed from at least three separate genes. At least four mRNA splice variants for each dynamin have been described. Dynamins contain several conserved regions including the conserved, amino-terminal GTPase domain, a centrally located membrane-binding plekstrin homology domain (PHD), and a coiled-coil region located in front of a proline-rich domain (PRD). The PRD is thought to mediate interactions between dynamin and numerous other cellular proteins. Dynamin I is expressed exclusively in neurons, dynamin II is ubiquitously expressed, and dynamin III is thought to be restricted to expression in the brain, testis, heart, and lung. The dynamins participate in the cellular process of clathrin-mediated and fluid-phase endocytosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Dynamin 3
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation PBS with 1 mg/mL BSA and 0.05% sodium azide
Gene Dnm3
Gene Accession No. Q08877, Q8BZ98, Q9UQ16
Gene Alias 9630020E24Rik; AW061159; B230343F03Rik; C530045C17; DNM3; Dyn3; Dyna III; dynamin 3; dynamin family member; Dynamin III; dynamin, testicular; dynamin-2; Dynamin-3; KIAA0820; mKIAA0820; T-dynamin; testicular dynamin
Gene Symbols Dnm3
Host Species Rabbit
Immunogen Synthetic Peptide: C P(623) D K S F T E N D E N G Q A E N F(639).
Purification Method Ammonium sulfate precipitation
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 103967, 171574, 26052
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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