Invitrogen™ Dynamin 3 Recombinant Rabbit Monoclonal Antibody (5X7T4)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA537890

Catalog No. PIMA537890

Description

Positive Samples: SH-SY5Y, Mouse testis, Mouse spinal cord, Mouse brain Immunogen sequence: ELLAQLYSSE DQNTLMEESA EQAQRRDEML RMYQALKEAL GIIGDISTAT VSTPAPPPVD DSWIQHSRRS PPPSPTTQRR PTLSAPLARP TSGRGPAPAI P.

The dynamins are a family of 100 kDa GTPases transcribed from at least three separate genes. At least four mRNA splice variants for each dynamin have been described. Dynamins contain several conserved regions including the conserved, amino-terminal GTPase domain, a centrally located membrane-binding plekstrin homology domain (PHD), and a coiled-coil region located in front of a proline-rich domain (PRD). The PRD is thought to mediate interactions between dynamin and numerous other cellular proteins. Dynamin I is expressed exclusively in neurons, dynamin II is ubiquitously expressed, and dynamin III is thought to be restricted to expression in the brain, testis, heart, and lung. The dynamins participate in the cellular process of clathrin-mediated and fluid-phase endocytosis.

Specifications

• Antigen: Dynamin 3
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8BZ98, Q9UQ16
• Gene Symbols: Dnm3
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 700-800 of human Dynamin 3 (Q9UQ16).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 5X7T4
• Conjugate: Unconjugated
• Gene: Dnm3
• Gene Alias: 9630020E24Rik; AW061159; B230343F03Rik; C530045C17; DNM3; Dyn3; Dyna III; dynamin 3; dynamin family member; Dynamin III; dynamin, testicular; dynamin-2; Dynamin-3; KIAA0820; mKIAA0820; T-dynamin; testicular dynamin
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 103967, 26052
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid