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Tocris Bioscience™ Dynapyrazole A
GREENER_CHOICE

Catalog No. 689625
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Hedgehog signaling inhibitor; dynein inhibitor

Dynapyrazole A is a dynein inhibitor. Inhibits dynein 1 and dynein 2-dependent microtubule gliding (IC50 values are 2.3 and 2.6 μM, respectively). Inhibits hedgehog signaling in vitro (IC50 = 1.9 μM). Displays reversible inhibition of retrograde and anterograde intraflagellar transport in Chlamydomonas; displays stronger inhibition of retrograde transport.

Specifications

Chemical Name or Material 2-[1-(4-Chlorophenyl)cyclopropyl]-4,5-dihydro-7-iodo-5-oxopyrazolo[1,5-a]quinazoline-3-carbonitrile
CAS 2226517-75-3
Quantity 25 mg
Target Hedgehog Signaling Inhibitors
Molecular Formula C20H12ClIN4O
Formula Weight 3333
Purity 98%
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