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Tocris™ Dynapyrazole A

Hedgehog signaling inhibitor; dynein inhibitor

Manufacturer:  Tocris™ 6896/25

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Catalog No. 68-962-5


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Description

Description

Dynapyrazole A is a dynein inhibitor. Inhibits dynein 1 and dynein 2-dependent microtubule gliding (IC50 values are 2.3 and 2.6 μM, respectively). Inhibits hedgehog signaling in vitro (IC50 = 1.9 μM). Displays reversible inhibition of retrograde and anterograde intraflagellar transport in Chlamydomonas; displays stronger inhibition of retrograde transport.
Specifications

Specifications

2-[1-(4-Chlorophenyl)cyclopropyl]-4,5-dihydro-7-iodo-5-oxopyrazolo[1,5-a]quinazoline-3-carbonitrile
C20H12ClIN4O
Hedgehog Signaling Inhibitors
25 mg
3333
98%
2226517-75-3
Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

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