Tocris™ Dynapyrazole A
Hedgehog signaling inhibitor; dynein inhibitor
Manufacturer: Tocris™ 6896/25
DescriptionDynapyrazole A is a dynein inhibitor. Inhibits dynein 1 and dynein 2-dependent microtubule gliding (IC50 values are 2.3 and 2.6 μM, respectively). Inhibits hedgehog signaling in vitro (IC50 = 1.9 μM). Displays reversible inhibition of retrograde and anterograde intraflagellar transport in Chlamydomonas; displays stronger inhibition of retrograde transport.
|Hedgehog Signaling Inhibitors|
Safety and Handling
Recommended Storage : Store at -20°C
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