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Invitrogen™ DYNC1H1 Polyclonal Antibody
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Catalog No. PIPA5117280
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100 μL
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PIPA5117280 100 μL
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Catalog No. PIPA5117280 Supplier Invitrogen™ Supplier No. PA5117280
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Description

Rabbit Polyclonal Antibody

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DYNC1H1 (Dynein Cytoplasmic 1 Heavy Chain 1) is a gene that encodes a protein belonging to the dynein family, which are motor proteins critical for various cellular processes. Dyneins are responsible for retrograde intracellular transport along microtubules, meaning they move cargo from the periphery of the cell towards the nucleus. The DYNC1H1 protein is a heavy chain component of cytoplasmic dynein 1, which plays a key role in the movement of organelles, vesicles, and other cellular components. Mutations in DYNC1H1 have been associated with several neurological disorders, including spinal muscular atrophy with lower extremity predominance (SMA-LED) and Charcot-Marie-Tooth disease type 2O (CMT2O). Research into DYNC1H1 continues to uncover its involvement in cellular mechanics and its implications in various genetic conditions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DYNC1H1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.89 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene dync1h1
Gene Accession No. Q14204
Gene Alias 9930018I23Rik; AI894280; CMT2O; cytoplasmic dynein 1 heavy chain 1; Cytoplasmic dynein heavy chain 1; cytoplasmic dynein heavy chain polypeptide 1; Dhc1; DHC1a; DNCH1; Dnchc1; DNCL; Dnec1; DNECL; DYHC; DYNC1H1; dynein cytoplasmic 1 heavy chain 1; dynein heavy chain, cytosolic; dynein heavy chain, retrograde transport; dynein, cytoplasmic 1, heavy chain 1; dynein, cytoplasmic, heavy chain 1; dynein, cytoplasmic, heavy polypeptide 1; fk70a07; HL-3; KIAA0325; legs at odd angle; Loa; MAP 1C; MAP1C; mKIAA0325; p22; SMALED1; sprawling; Swl; wu:fk70a07
Gene Symbols dync1h1
Host Species Rabbit
Immunogen Recombinant protein corresponding to human DYNC1H1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1778
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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