Invitrogen™ DYNC1I1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529504

Catalog No. PIPA529504

Description

Recommended positive controls: Jurkat, NCI-H929. Predicted reactivity: Mouse (96%), Rat (96%), Rhesus Monkey (99%), Bovine (85%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.

Specifications

• Antigen: DYNC1I1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DYNC1I1
• Gene Alias: Cytoplasmic dynein 1 intermediate chain 1; cytoplasmic dynein intermediate chain 1; cytoplasmic dynein intermediate chain 1 isoform 1.6; DH IC-1; DHIC-1; DIC; Dnci 1; DNCI1; Dncic1; Dync1i1; dynein cytoplasmic 1 intermediate chain 1; dynein intermediate chain 1, cytosolic; Dynein intermediate chain 1, cytosolic (DH IC-1) (Cytoplasmic dynein intermediate chain 1); dynein, cytoplasmic 1, intermediate chain 1; dynein, cytoplasmic, intermediate chain 1; dynein, cytoplasmic, intermediate polypeptide 1; IC74
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1780
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.74 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O14576
• Gene Symbols: DYNC1I1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 57 and 325 of Human DYNC1I1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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