Invitrogen™ DYNC1I1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116993

Catalog No. PIPA5116993

Description

Positive Samples: Jurkat, SH-SY5Y, HeLa, Mouse testis, Mouse brain, Mouse skeletal muscle, Rat brain, Rat testis Immunogen sequence: MSDKSDLKAE LERKKQRLAQ IREEKKRKEE ERKKKEADMQ QKKEPVQDDS DLDRKRRETE ALLQSIGISP EPPLVPTPMS PSSKSVSTPS EAGSQDSGDL GPLTRTLQWD TDPSVLQLQS DSELGRRLHK LGVSKVTQVD FLPREVVSYS KETQTPLATH QSEEDEEDEE MVESKVGQDS ELENQDKKQE VKEAPPRELT EEEKQQILHS EEFLIFFDRT.

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.

Specifications

• Antigen: DYNC1I1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DYNC1I1
• Gene Alias: Cytoplasmic dynein 1 intermediate chain 1; cytoplasmic dynein intermediate chain 1; cytoplasmic dynein intermediate chain 1 isoform 1.6; DH IC-1; DHIC-1; DIC; Dnci 1; DNCI1; Dncic1; Dync1i1; dynein cytoplasmic 1 intermediate chain 1; dynein intermediate chain 1, cytosolic; Dynein intermediate chain 1, cytosolic (DH IC-1) (Cytoplasmic dynein intermediate chain 1); dynein, cytoplasmic 1, intermediate chain 1; dynein, cytoplasmic, intermediate chain 1; dynein, cytoplasmic, intermediate polypeptide 1; IC74
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13426, 1780, 29564
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O14576, O88485, Q63100
• Gene Symbols: DYNC1I1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human DYNC1I1 (NP_0011290281).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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