Invitrogen™ Dynein Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589506

Catalog No. PIPA589506

Description

Immunogen sequence: MSDRKAVIKN ADMSEDMQQD AVDCATQAME KYNIEKDIAA YIKKEFDKKY NPTWHCIVGR NFGSYVTHET KHFIYFYLGQ VAILLFKSG; Positive Samples: Mouse brain, Mouse kideny, Rat brain; Cellular Location: Cytoplasm, cytoskeleton.

The directed movement of membrane-bounded organelles is an important process for various cellular functions including membrane transport, secretion, and axonal transport. Cytoplasmic dynein, a ubiquitous minus end-directed microtubule-based motor protein, is believed to be responsible for the retrograde transport of membranous organelles from the synapse to the cell body in fast axonal transport. The cytoplasmic dynein complex is composed of two ~530 kDa heavy chains, and intermediate chains of ~74 kDa and ~53-59 kDa.

Specifications

• Antigen: Dynein
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DYNLL2
• Gene Alias: 1700064A15Rik; 6720463E02Rik; 8 kDa dynein light chain; 8 kDa dynein light chain b; 8kD LC; 8kDa LC; 8kDLC; C87222; CDLC2; cytoplasmic dynein light polypeptide; cytoplasmic dynein light polypeptide 1; cytoplasmic light-chain dynein; cytosolic DH IC-1; DLC1; Dlc2; DLC8; DLC8b; DNCL1; DNCL1B; Dnclc1; dynein LC8; dynein light chain 1, cytoplasmic; Dynein light chain 2, cytoplasmic; dynein light chain LC8-type 1; Dynein light chain LC8-type 2; dynein light chain-2; dynein, cytoplasmic, light chain 1; dynein, cytoplasmic, light peptide; dynein, cytoplasmic, light polypeptide 1; dynein, light chain, LC8-type 1; dynein, light chain, LC8-type 2; DYNLL1; DYNLL2; HDLC1; LC8; LC8; PIN; LC8a; LOC540369 protein; mPIN; PIN; Protein inhibitor of neuronal nitric oxide synthase; protein inhibitor of nitric oxide synthase; radial spoke 22 homolog; RSPH22; similar to cytoplasmic dynein light chain 1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 140734, 140735, 56455, 58945, 68097, 8655
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.18 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P63167, P63168, P63170, Q78P75, Q96FJ2, Q9D0M5
• Gene Symbols: DYNLL1, DYNLL2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-89 of human DYNLL2 (NP_5424081).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG