Invitrogen™ DYNLL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100898

Catalog No. PIPA5100898

Description

Antibody detects endogenous levels of total DYNLL1.

Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1, 200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. DYNLL1 is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity.

Specifications

• Antigen: DYNLL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DYNLL1
• Gene Alias: 8 kDa dynein light chain; 8kD LC; 8kDa LC; 8kDLC; CDLC2; cytoplasmic dynein light polypeptide; cytoplasmic dynein light polypeptide 1; DLC1; DLC1DNCLC1; DLC8; DLC8MGC126137; DNCL1; DNCL1MGC126138; Dnclc1; dynein LC8; dynein light chain 1, cytoplasmic; dynein light chain 2; dynein light chain LC8-type 1; dynein, cytoplasmic, light chain 1; dynein, cytoplasmic, light peptide; dynein, cytoplasmic, light polypeptide 1; dynein, light chain, LC8-type 1; dynein, light chain, LC8-type 2; Dynll1; dynll2; H LC8; hdlc1; LC8; LC8a; LC8-type 1; MGC126137; MGC126138; mPIN; PIN; PINLC8a; Protein inhibitor of neuronal nitric oxide synthase; protein inhibitor of nitric oxide synthase; similar to cytoplasmic dynein light chain 1; wu:fd56c09; zgc:73406
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56455, 58945, 8655
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P63167, P63168, P63170
• Gene Symbols: DYNLL1
• Immunogen: A synthesized peptide derived from human DYNLL1(Accession P63167), corresponding to amino acid residues M1-D47.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov