Invitrogen™ DYNLRB1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103808

Catalog No. PIPA5103808

Description

Antibody detects endogenous levels of total DYNLRB1.

The DYNLRB1 gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18.

Specifications

• Antigen: DYNLRB1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Dynlrb1
• Gene Alias: 2010012N15Rik; 2010320M17Rik; 9430076K19Rik; AV124457; BITH; bithoraxoid-like protein; BLP; Dncl2a; DNLC2A; dynein light chain 2A, cytoplasmic; Dynein light chain roadblock-type 1; dynein, cytoplasmic, light chain 2A; dynein, cytoplasmic, light polypeptide 2A; dynein, light chain, roadblock-type 1; dynein-associated protein Km23; dynein-associated protein RKM23; DYNLRB1; HSPC162; hypothetical protein LOC513342; km23; km23-1; Roadblock domain-containing protein 1; ROBL/LC7-like 1; robl/LC7-like protein; ROBLD1; similar to dynein, cytoplasmic, light polypeptide 2A; zgc:56335
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170714, 67068, 83658
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P62627, P62628, Q9NP97
• Gene Symbols: Dynlrb1
• Immunogen: A synthesized peptide derived from human DYNLRB1(Accession Q9NP97), corresponding to amino acid residues I50-E96.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov