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Invitrogen™ DYRK1A Polyclonal Antibody
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Catalog No. PIPA587461
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100 μL
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PIPA587461 100 μL
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Catalog No. PIPA587461 Supplier Invitrogen™ Supplier No. PA587461
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LGNRTRPRVY NSPTNSSSTQ DSMEVGHSHH SMTSLSSSTT SSSTSSSSTG NQGNQAYQNR PVAANTLDFG QNGAMDVNLT VYSNPRQETG IAGHPTYQFS ANTGPAHYMT EGHLTMRQGA DREESPMTGV CVQQSPVASS; Positive Samples: NCI-H460, 293T, K-562, HeLa, Jurkat, Mouse brain, Rat brain; Cellular Location: Nucleus speckle.

DYRK1A is a dual specificity kinase involved in cell proliferation. The gene for DYRK1A is located in the Down syndrome critical region of chromosome 21, and has been implicated in the pathogenesis of this disease. DYRK1A catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DYRK1A
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.8 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene DYRK1A
Gene Accession No. Q13627
Gene Alias 2310043O08Rik; D16Ertd272e; D16Ertd493e; dual specificity tyrosine phosphorylation regulated kinase 1A; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; dual specificity tyrosine-phosphorylation-regulated kinase 1A; Dual specificity YAK1-related kinase; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a; Dyrk; DYRK1; Dyrk1a; ENSMUSG00000074897; Gm10783; hMNB; HP86; mmb; MNB; mnb protein kinase homolog hp86; MNB/DYRK protein kinase; MNBH; MP86; MRD7; OTTHUMP00000109090; Protein kinase minibrain homolog; PSK47; RP86; serine/threonine kinase MNB; serine/threonine-specific protein kinase
Gene Symbols DYRK1A
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 624-763 of human DYRK1A (NP_0013872).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1859
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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