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Invitrogen™ DYRK1A Polyclonal Antibody
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Catalog No. PIPA5142885
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100 μg
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Catalog No. Quantity
PIPA5142885 100 μg
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Catalog No. PIPA5142885 Supplier Invitrogen™ Supplier No. PA5142885
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Description

Goat Polyclonal Antibody

Additional Information: This antibody is expected to recognize all reported isoforms (NP_001387.2; NP_569120.1; NP_567824.1; NP_569122.1). This antibody is not expected to cross-react with DYRK1B. This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.

DYRK1A is a dual specificity kinase involved in cell proliferation. The gene for DYRK1A is located in the Down syndrome critical region of chromosome 21, and has been implicated in the pathogenesis of this disease. DYRK1A catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DYRK1A
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene DYRK1A
Gene Accession No. Q13627
Gene Alias 2310043O08Rik; D16Ertd272e; D16Ertd493e; dual specificity tyrosine phosphorylation regulated kinase 1A; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; dual specificity tyrosine-phosphorylation-regulated kinase 1A; Dual specificity YAK1-related kinase; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a; Dyrk; DYRK1; Dyrk1a; ENSMUSG00000074897; Gm10783; hMNB; HP86; mmb; MNB; mnb protein kinase homolog hp86; MNB/DYRK protein kinase; MNBH; MP86; MRD7; OTTHUMP00000109090; Protein kinase minibrain homolog; PSK47; RP86; serine/threonine kinase MNB; serine/threonine-specific protein kinase
Gene Symbols DYRK1A
Host Species Goat
Immunogen Peptide with sequence PHSHQYSDRRQPN-C.
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1859
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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