DYRK1A Polyclonal Antibody, Bethyl Laboratories

Catalog No.	Quantity
50-156-6099	20 μL

Catalog No. 50-156-6099 Supplier Bethyl Laboratories, Inc Supplier No. A303802AT

Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, X. laevis and X. tropicalis

DYRK1A is a member of the dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family and is thought to be involved in neuronal differentiation, neurodegenerative diseases, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. DYRK1A phosphorylates several transcription factors such as p53, leading to inhibition of embryonic neuronal cell proliferation. DYRK1A associates with multiple proteins, including SPRED1 and SPRED2; this association appears to inhibit the phosphorylation activity of DYRK1A. Recent evidence also suggests that DYRK1A may be involved in the replication of HIV-1.

Specifications

• Antigen: DYRK1A
• Applications: Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene: DYRK1A
• Gene Accession No.: Q13627
• Gene Alias: DYRK1A, DYRK1, HP86, MNB
• Gene Symbols: DYRK1A
• Host Species: Rabbit
• Immunogen: Between 713 and 763
• Purification Method: Antigen affinity chromatography
• Quantity: 20 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1859
• Target Species: Human
• Content And Storage: 4° C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG