Invitrogen™ DYRK1B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA585318

Catalog No. PIPA585318

Description

Keep as concentrated solution. Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (92%), Rhesus Monkey (99%), Bovine (99%). Positive Control: mouse testis, rat testis. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

DYRK1B is a member of the DYRK family of protein kinases and is proposed to be involved in nuclear functions. Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. DYRK1B encodes the integrin beta 4 subunit, a receptor for the laminins. Mutations in DYRK1B are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for DYRK1B.

Specifications

• Antigen: DYRK1B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DYRK1B
• Gene Alias: AOMS3; dual specificity tyrosine phosphorylation regulated kinase 1B; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; dual specificity tyrosine-phosphorylation-regulated kinase 1B; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; DYRK1B; DYRKB; Minibrain-related kinase; Mirk; Mirk protein kinase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13549, 308468, 9149
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9Y463, Q9Z188
• Gene Symbols: DYRK1B
• Immunogen: Recombinant protein encompassing a sequence within the center region of human DYRK1B.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov