Invitrogen™ DYRK2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521125

Catalog No. PIPA521125

Description

A suggested positive control is 293 cell lysate. PA5-21125 can be used with blocking peptide PEP-1239.

DYRK2 (also known as dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2) belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development and is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 expressed in E. coli demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. DYRK2 also regulates p53 to induce apoptosis in response to DNA damage.

Specifications

• Antigen: DYRK2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DYRK2
• Gene Alias: 1810038L18Rik; dual specificity tyrosine phosphorylation regulated kinase 2; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 2; dual specificity tyrosine-phosphorylation-regulated kinase 2; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2; dyrk2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8445
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q92630
• Gene Symbols: DYRK2
• Immunogen: An 18 amino acid peptide near the carboxy terminus of human DYRK2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov