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DYRK3 Monoclonal Antibody, Invitrogen™

Catalog No. MA191870
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50 μg
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Catalog No. Quantity
MA191870 50 μg
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Catalog No. MA191870 Supplier Thermo Scientific Supplier No. MA191870

Description

Mouse Monoclonal Antibody

Recommended positive controls: 3T3/A31 RIPA lysate.

DYRK3 belongs to the DYRK family of dual-specificity protein kinases that catalyze phosphorylation of serine/threonine and tyrosine residues. The members of this family share structural similarity, but differ in their substrate specificity, suggesting their involvement in different cellular functions. DYRK3 is a negative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DYRK3
Applications ELISA, Immunoprecipitation, Western Blot
Classification Monoclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 0.15M NaCl, 30% glycerol and no preservative; pH 7.4
Gene DYRK3
Gene Accession No. O43781, Q4V8A3, Q922Y0
Gene Alias BC006704; dual specificity tyrosine phosphorylation regulated kinase 3; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 3; dual specificity tyrosine-phosphorylation-regulated kinase 3; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5; dyrk3; dyrk3 {ECO:0000312; DYRK5; EMBL:AAH97474.1}; hYAK3-2; KSR; protein kinase Dyrk3; RED; REDK; regulatory erythroid kinase; RP11-343H5.2; RSU2
Gene Symbols DYRK3
Host Species Mouse
Immunogen Fusion protein, corresponding to amino acids 118-248 of Rat KSR.
Purification Method Protein G
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 226419, 304775, 8444
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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