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Invitrogen™ DYRK3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5103282
Description
Antibody detects endogenous levels of total DYRK3.
DYRK3 belongs to the DYRK family of dual-specificity protein kinases that catalyze phosphorylation of serine/threonine and tyrosine residues. The members of this family share structural similarity, but differ in their substrate specificity, suggesting their involvement in different cellular functions. DYRK3 is a negative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling.
Specifications
DYRK3 | |
Polyclonal | |
Unconjugated | |
DYRK3 | |
BC006704; dual specificity tyrosine phosphorylation regulated kinase 3; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 3; dual specificity tyrosine-phosphorylation-regulated kinase 3; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5; dyrk3; dyrk3 {ECO:0000312; DYRK5; EMBL:AAH97474.1}; hYAK3-2; KSR; protein kinase Dyrk3; RED; REDK; regulatory erythroid kinase; RP11-343H5.2; RSU2 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
226419, 304775, 8444 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
O43781, Q4V8A3, Q922Y0 | |
DYRK3 | |
A synthesized peptide derived from human DYRK3(Accession O43781), corresponding to amino acid residues S453-L503. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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