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Invitrogen™ DYRK3 Polyclonal Antibody
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Catalog No. PIPA521875
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100 μL
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Catalog No. Quantity
PIPA521875 100 μL
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Catalog No. PIPA521875 Supplier Invitrogen™ Supplier No. PA521875
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, H1299, HepG2, Raji, mouse liver. Predicted reactivity: Mouse (92%), Rat (94%), Chimpanzee (99%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

DYRK3 belongs to the DYRK family of dual-specificity protein kinases that catalyze phosphorylation of serine/threonine and tyrosine residues. The members of this family share structural similarity, but differ in their substrate specificity, suggesting their involvement in different cellular functions. DYRK3 is a negative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DYRK3
Applications Western Blot
Classification Polyclonal
Concentration 0.68 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene DYRK3
Gene Accession No. O43781, Q922Y0
Gene Alias BC006704; dual specificity tyrosine phosphorylation regulated kinase 3; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 3; dual specificity tyrosine-phosphorylation-regulated kinase 3; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5; dyrk3; dyrk3 {ECO:0000312; DYRK5; EMBL:AAH97474.1}; hYAK3-2; KSR; protein kinase Dyrk3; RED; REDK; regulatory erythroid kinase; RP11-343H5.2; RSU2
Gene Symbols DYRK3
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Dyrk3. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 226419, 8444
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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