Invitrogen™ Dystrophin Monoclonal Antibody (C4)

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA541582	Invitrogen™ MA541582	200 μL
PIMA543846	Invitrogen™ MA543846	20 μL

Description

Dystrophin Monoclonal Antibody for Western Blot

Dystrophin is the 427kDa protein product of the DMB/BMD gene located on the X chromosome at position Xp21. Western blotting and immunohistochemistry are the two established methods for the detection of abnormalities of dystrophin expression in muscle biopsies. Dystrophin abnormalities are thought to occur in 100% of patients with DMD/BMD, although genetic abnormalities may only be detected in up to 65% of cases.

Specifications

• Antigen: Dystrophin
• Concentration: 1 mg/mL
• Applications: Western Blot, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: P11532
• Gene ID (Entrez): 1756
• Immunogen: Recombinant protein Dystrophin. The antigen corresponds to amino acid range 253-597 of the target protein.
• Product Type: Antibody

• Clone: C4
• Content And Storage: -20°C
• Classification: Monoclonal
• Form: Liquid
• Isotype: IgG2b κ
• Target Species: Human
• Gene: DMD
• Gene Alias: apodystrophin-3; apodystrophin-I; BMD; CMD3B; dmd; dmd.1; dmd.1.L; DNADMD1; Dp427; Dp71; Duchenne muscular dystrophy (DMD); DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; DXSmh7; DXSmh9; dys; Dystrophin; dystrophin Dp40; dystrophin Dp71 isoform; dystrophin Dp71a; dystrophin Dp71ab; dystrophin Dp71b; dystrophin, gene 1 L homeolog; dystrophin, muscular dystrophy; GS1-19O24.1; mdx; MRX85; Muscular dystrophy Duchenne and Becker types; OTTHUMP00000215592; pke; utrn; utrophin; XELAEV_18012903mg; X-linked muscular dystrophy
• Gene Symbols: DMD
• Primary or Secondary: Primary
• Purification Method: Protein A/G