Dystrophin Monoclonal Antibody (C8), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA550847

Catalog No. FEMA550847

Description

Dystrophin is the 427kDa protein product of the DMB/BMD gene located on the X chromosome at position Xp21. Western blotting and immunohistochemistry are the two established methods for the detection of abnormalities of dystrophin expression in muscle biopsies. Dystrophin abnormalities are thought to occur in 100% of patients with DMD/BMD, although genetic abnormalities may only be detected in up to 65% of cases.

Specifications

• Antigen: Dystrophin
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
• Gene Accession No.: P11530, P11532, Q5GN48
• Gene Symbols: DMD
• Immunogen: Recombinant Human DMD protein, Ile253-Lys597 (Accession #P11532)
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human, Pig, Rat
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Clone: C8
• Conjugate: Unconjugated
• Gene: DMD
• Gene Alias: apodystrophin-3, apodystrophin-I, BMD, CMD3B, dmd, dmd.1, dmd.1.L, DNADMD1, Dp427, Dp71, Duchenne muscular dystrophy (DMD), DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, DXSmh7, DXSmh9, dys, Dystrophin, dystrophin Dp40, dystrophin Dp71 isoform, dystrophin Dp71a, dystrophin Dp71ab, dystrophin Dp71b, dystrophin, gene 1 L homeolog, dystrophin, muscular dystrophy, GS1-19O24.1, mdx, MRX85, Muscular dystrophy Duchenne and Becker types, OTTHUMP00000215592, pke, utrn, utrophin, XELAEV_18012903mg, X-linked muscular dystrophy
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 1756, 24907, 497636
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Isotype: IgG2a κ