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Invitrogen™ Dystrophin Monoclonal Antibody (C8), Invitrogen™

Catalog No. FEMA550848
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200 μL
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FEMA550848 20 μL
FEMA550847 200 μL
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Catalog No. FEMA550848 Supplier Invitrogen™ Supplier No. MA550848
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Description

Mouse Monoclonal Antibody

Dystrophin is the 427kDa protein product of the DMB/BMD gene located on the X chromosome at position Xp21. Western blotting and immunohistochemistry are the two established methods for the detection of abnormalities of dystrophin expression in muscle biopsies. Dystrophin abnormalities are thought to occur in 100% of patients with DMD/BMD, although genetic abnormalities may only be detected in up to 65% of cases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Dystrophin
Applications Immunohistochemistry (Paraffin), Western Blot, Western Blot
Classification Monoclonal
Clone C8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
Gene DMD
Gene Accession No. P11530, P11532, Q5GN48
Gene Alias apodystrophin-3; apodystrophin-I; BMD; CMD3B; dmd; dmd.1; dmd.1.L; DNADMD1; Dp427; Dp71; Duchenne muscular dystrophy (DMD); DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; DXSmh7; DXSmh9; dys; Dystrophin; dystrophin Dp40; dystrophin Dp71 isoform; dystrophin Dp71a; dystrophin Dp71ab; dystrophin Dp71b; dystrophin, gene 1 L homeolog; dystrophin, muscular dystrophy; GS1-19O24.1; mdx; MRX85; Muscular dystrophy Duchenne and Becker types; OTTHUMP00000215592; pke; utrn; utrophin; XELAEV_18012903mg; X-linked muscular dystrophy
Gene Symbols DMD
Host Species Mouse
Immunogen Recombinant Human DMD protein, Ile253-Lys597 (Accession #P11532).
Purification Method Protein A/G
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1756, 24907, 497636
Target Species Human, Rat, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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