Dystrophin Monoclonal Antibody (MANDYS8), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA549307

Catalog No. PIMA549307

Description

Add 0.2 mL of PBS buffer will yield a concentration of 500 μg/mL.

Dystrophin is the 427kDa protein product of the DMB/BMD gene located on the X chromosome at position Xp21. Western blotting and immunohistochemistry are the two established methods for the detection of abnormalities of dystrophin expression in muscle biopsies. Dystrophin abnormalities are thought to occur in 100% of patients with DMD/BMD, although genetic abnormalities may only be detected in up to 65% of cases.

Specifications

• Antigen: Dystrophin
• Classification: Monoclonal
• Concentration: 100 μg/mL
• Formulation: ascites diluted in 1.2% sodium acetate with 2MG BSA and 0.01MG sodium azide
• Gene Accession No.: P11530, P11531, P11532
• Gene Symbols: DMD
• Immunogen: Recombinant human dystrophin fragment.
• Regulatory Status: RUO
• Gene ID (Entrez): 100355731, 13405, 1756, 24907
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Isotype: IgG2b

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: MANDYS8
• Conjugate: Unconjugated
• Gene: DMD
• Gene Alias: apodystrophin-3; apodystrophin-I; BMD; CMD3B; dmd; dmd.1; dmd.1.L; DNADMD1; Dp427; Dp71; Duchenne muscular dystrophy (DMD); DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; DXSmh7; DXSmh9; dys; Dystrophin; dystrophin Dp40; dystrophin Dp71 isoform; dystrophin Dp71a; dystrophin Dp71ab; dystrophin Dp71b; dystrophin, gene 1 L homeolog; dystrophin, muscular dystrophy; GS1-19O24.1; mdx; MRX85; Muscular dystrophy Duchenne and Becker types; OTTHUMP00000215592; pke; utrn; utrophin; XELAEV_18012903mg; X-linked muscular dystrophy
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rabbit, Rat
• Form: Lyophilized