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Invitrogen™ Dystrophin Polyclonal Antibody

Rabbit Polyclonal Antibody

$599.50 - $835.50

Specifications

Antigen Dystrophin
Concentration Conc. not determined
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Classification Polyclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
01-673-387
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Invitrogen™
PA137587
1 mL
Each for $835.50
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PIPA532388
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Invitrogen™
PA532388
500 μL
Each for $599.50
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Description

Description

This antibody is predicted to react with bovine, chicken, canine and porcine based on sequence homology. Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is skeletal muscle tissue.

Dystrophin is the 427kDa protein product of the DMB/BMD gene located on the X chromosome at position Xp21. Western blotting and immunohistochemistry are the two established methods for the detection of abnormalities of dystrophin expression in muscle biopsies. Dystrophin abnormalities are thought to occur in 100% of patients with DMD/BMD, although genetic abnormalities may only be detected in up to 65% of cases.
Specifications

Specifications

Dystrophin
-20°C, Avoid Freeze/Thaw Cycles
Polyclonal
Liquid
IgG
Human, Mouse
DMD
apodystrophin-3; apodystrophin-I; BMD; CMD3B; dmd; dmd.1; dmd.1.L; DNADMD1; Dp427; Dp71; Duchenne muscular dystrophy (DMD); DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; DXSmh7; DXSmh9; dys; Dystrophin; dystrophin Dp40; dystrophin Dp71 isoform; dystrophin Dp71a; dystrophin Dp71ab; dystrophin Dp71b; dystrophin, gene 1 L homeolog; dystrophin, muscular dystrophy; GS1-19O24.1; mdx; MRX85; Muscular dystrophy Duchenne and Becker types; OTTHUMP00000215592; pke; utrn; utrophin; XELAEV_18012903mg; X-linked muscular dystrophy
DMD
Primary
Antigen affinity chromatography
Conc. not determined
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
RUO
PBS with 1% BSA and 0.1% sodium azide; pH 7.6
P11531, P11532
13405, 1756
Synthetic peptide derived from C-terminus of human dystrophin.
Antibody
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