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Tocris Bioscience™ E 64
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Catalog No. 520810
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Catalog No. Quantity
52-081-0 10 mg
52-085-0 50 mg
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Catalog No. 52-081-0 Supplier Tocris Bioscience™ Supplier No. 5208/10
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Description

Potent and irreversible cysteine protease inhibitor

E 64 is a potent and irreversible cysteine protease inhibitor (IC50 values are 1.4, 2.5 and 4.1 nM for cathepsin K, L and S respectively. Also inhibits papain, calpain, cathepsin B and cathepsin H. Has no effect on serine proteases. Reduces HSC-3 tongue cancer cell invasion and induces oxidative stress and apoptosis in filarial parasites. Also inhibits autophagy-associated lysosomal degradation in vitro.

Specifications

Quantity 10 mg
Product Type E 64
Purity >98%
Molecular Weight (g/mol) 357.41
Inhibitors E 64

For Research Use Only

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