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  5. Tocris Bioscience™ E 7820

Tocris Bioscience™ E 7820
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Catalog No. 678510
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

α2 integrin inhibitor; anti-angiogenic

E 7820 is a α2 integrin inhibitor. Inhibits angiogenesis in vitro (IC50 = 0.11 - 0.25 μM). Also inhibits growth of human colorectal cancer cell lines. Enhances efficacy of erlotinib in a non-small-cell lung cancer xenograft model. Also acts as a molecular glue to induce proteosomal degradation of mRNA splicing factor RBM39.

Specifications

Chemical Name or Material 3-Cyano-N-(3-cyano-4-methyl-1 H-indol-7-yl)benzenesulfonamide
CAS 289483-69-8
Quantity 10 mg
Target Integrin Receptor Inhibitors
Molecular Formula C17H12N4O2S
Formula Weight 336.37
Purity 98%
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