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Invitrogen™ E2F2 Polyclonal Antibody
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Catalog No. PIPA523983
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400 μL
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Catalog No. Quantity
PIPA523983 400 μL
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Catalog No. PIPA523983 Supplier Invitrogen™ Supplier No. PA523983
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Description

Rabbit Polyclonal Antibody

E2F2 Polyclonal Antibody for Western Blot

E2F2 is a member of the E2Ffamily of transcription factors. The E2F family plays a crucialrole in the control of cell cycle and action of tumor suppressorproteins and is also a target of the transforming proteins of smallDNA tumor viruses. The E2F proteins contain several evolutionallyconserved domains found in most members of the family. Thesedomains include a DNA binding domain, a dimerization domain whichdetermines interaction with the differentiation regulatedtranscription factor proteins (DP), a transactivation domainenriched in acidic amino acids, and a tumor suppressor proteinassociation domain which is embedded within the transactivationdomain. This protein and another 2 members, E2F1 and E2F3, have anadditional cyclin binding domain. This protein binds specificallyto retinoblastoma protein pRB in a cell-cycle dependent manner, andit exhibits overall 46% amino acid identity to E2F1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen E2F2
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene E2F2
Gene Accession No. P56931, Q14209
Gene Alias E2F transcription factor 2; E2F2; E2F-2; LOW QUALITY PROTEIN: transcription factor E2F2; transcription factor E2F2
Gene Symbols E2F2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 258-286 amino acids from the central region of human E2F2.
Purification Method Antigen Affinity Chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1870, 242705
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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