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Invitrogen™ E2F3 Polyclonal Antibody
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Catalog No. PIPA584678
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PIPA584678 100 μL
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Catalog No. PIPA584678 Supplier Invitrogen™ Supplier No. PA584678
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TNNQDHNGNI PKPASKDLAS TNSGHSDCSV SMGNLSPLAS PANLLQQTED QIPSNLEGPF VNLLPPLLQE DYLL Highest antigen sequence indentity to the following orthologs: Rat - 95%, Mouse - 95%.

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen E2F3
Applications ChIP Assay, Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene E2F3
Gene Accession No. O00716
Gene Alias DKFZp686C18211; E2F transcription factor 3; E2f3; E2F-3; E2f3a; E2F3b; KIAA0075; MGC104598; RGD1561600; RP1-177P22.2; Transcription factor E2F3
Gene Symbols E2F3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human E2F3. Recombinant protein control fragment (Product #RP-107394).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1871
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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