E2F5 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-4090	100 μL

Catalog No. 50-198-4090 Supplier Bioss Supplier No. BS1734R

Description

Rabbit Polyclonal Antibody

E2F5 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms.

Specifications

• Antigen: E2F5
• Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: E2F5
• Gene Accession No.: Q15329
• Gene Alias: AU024671; E2F transcription factor 5; E2F transcription factor 5, p130-binding; E2f5; E2F-5; Transcription factor E2F5
• Gene Symbols: E2F5
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human E2F5 .
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1875
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG