Invitrogen™ E4F1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA567167

Catalog No. PIPA567167

Description

Immunogen sequence: RHLKSLTPCTE KIRFSVSKDV VVSKEDARAG SGAGAAGLGT ATSSVTGEPI ETSPVIHLVT DAKGTVIHEV HVQM Highest antigen sequence identity to the following orthologs - mouse 77%, rat 79%.

May function as a transcriptional repressor. May also function as a ubiquitin ligase mediating ubiquitination of chromatin-associated TP53. Functions in cell survival and proliferation through control of the cell cycle. Functions in the p53 and pRB tumor suppressor pathways and regulates the cyclin CCNA2 transcription.; FUNCTION: Identified as a cellular target of the adenoviral oncoprotein E1A, it is required for both transcriptional activation and repression of viral genes.

Specifications

• Antigen: E4F1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: E4F1
• Gene Alias: deoxyribonuclease 1-like 2; Dnase1l2; E4F; E4F transcription factor 1; E4F1; p120E4F; p50E4F; phi-AP3; putative E3 ubiquitin-protein ligase E4F1; RING-type E3 ubiquitin transferase E4F1; Transcription factor E4F; transcription factor E4F1; Transcription factor phi AP3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1877
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q66K89
• Gene Symbols: E4F1
• Immunogen: Recombinant Human E4F1. Recombinant protein control fragment (Product #RP-105531).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov