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EAAT2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501733877 Shop All Proteintech Group Inc Products
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50-173-3877 150 μL
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Catalog No. 50-173-3877 Supplier Proteintech Group Inc Supplier No. 225151AP150UL
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Rabbit Polyclonal Antibody

Excitatory amino acid transporter 2 (EAAT2) is a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis (ALS.) Alternatively spliced transcript variants of this gene have been identified.

Specifications

Antigen EAAT2
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.19 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SLC1A2
Gene Accession No. P31596, P43004, P43006
Gene Alias EAAT2, GLT 1, GLT1, SLC1A2
Gene Symbols SLC1A2
Host Species Rabbit
Immunogen EAAT2 Fusion Protein Ag18247
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20511, 29482, 6506
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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