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EAAT2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984107
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100 μL
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50-198-4107 100 μL
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Catalog No. 50-198-4107 Supplier Bioss Supplier No. BS1751R
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Description

Rabbit Polyclonal Antibody

Excitatory amino acid transporter 2 (EAAT2) is a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis (ALS.) Alternatively spliced transcript variants of this gene have been identified.

Specifications

Antigen EAAT2
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene SLC1A2
Gene Accession No. P43004
Gene Alias 1700091C19Rik; 2900019G14Rik; AI159670; EAAT2; EAAT2 variant mEAAT2/5UT5; Excitatory amino acid transporter 2; excitotoxic amino acid transporter 2; glial high affinity glutamate transporter; Glt; GLT1; GLT-1; GLT1a; GLT1b; GLT1c; glutamate transporter 1c; Glutamate/aspartate transporter II; GLUT-R; HBGT; high affinity glucose transporter; MGLT1; OTTHUMP00000165209; OTTHUMP00000165210; SLC1A2; Sodium-dependent glutamate/aspartate transporter 2; solute carrier family 1 (glial high affinity glutamate transporter), member 2; Solute carrier family 1 member 2; solute carrier family 1, member 2
Gene Symbols SLC1A2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human EAAT2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6506
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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