EAAT4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-8319	150 μL

Catalog No. 50-172-8319 Supplier Proteintech Group Inc Supplier No. 128761AP150UL

Description

Rabbit Polyclonal Antibody

This antibody recognizes 60-70 kDa of EAAT4 in mouse brain and several other lysate.

Slc1a6 encodes a protein that is a glutamate transporters, also known as excitatory amino acid transporters (EAATs), are sodium- and potassium-dependent members of the solute carrier family 6 (SLC1), widely distributed throughout the brain. There are five EAAT subtypes, each with a specific distribution. Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Slc1a6 functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Slc1a6 also mediates Cl(-) flux that is not coupled to amino acid transport and this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Further, Slc1a6 [lays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (Probable). Diseases associated with SLC1A6 include Dicarboxylic Aminoaciduria.

Specifications

• Antigen: EAAT4
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.23 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: SLC1A6
• Gene Accession No.: O35544, O35921, P48664
• Gene Alias: EAAT4, SLC1A6
• Gene Symbols: SLC1A6
• Host Species: Rabbit
• Immunogen: EAAT4 Fusion Protein Ag3554
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 20513, 6511, 84012
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG