Invitrogen™ EAF2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552557

Catalog No. PIPA552557

Description

Immunogen sequence: GFSHLDRRER VLKLGESFEK QPRCAFHTVR YDFKPASIDT SSEGYLEVGE GEQVTITLPN IEGSTPPVTV FKGSKKPYLK ECILIINHDT GECRL Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 89%.

EAF1 and EAF2 can form a complex with ELL that targets the ternary elongation complex of Pol II, stimulating the rate of elongation. In addition, EAF1 and EAF2 are important for the stability of the NuA4 histone acetyltransferase complex, which transcriptionally activates certain genes by acetylation of Histones H4 and H2A. Both EAF1 and EAF2 are ubiquitously expressed members of the EAF family that colocalize with ELL to the the Cajal bodies and nuclear speckles. EAF1 contains a C-terminal region rich in aspartic acid, glutamic acid and serine residues. EAF2 is an androgen-response gene and can act as a potent apoptosis inducer.

Specifications

• Antigen: EAF2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Eaf2
• Gene Alias: AW048865; BM040; BM-040; Eaf2; Ehrlich S-II transcriptional activator factor; ELL associated factor 2; ELL-associated factor 2; Festa; FESTA-L; FESTA-S; testosterone regulated apoptosis inducer and tumor suppressor; testosterone-regulated apoptosis inducer and tumor suppressor protein; Traits; U19
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55840
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96CJ1
• Gene Symbols: Eaf2
• Immunogen: Recombinant protein corresponding to Human EAF2. Recombinant protein control fragment (Product #RP-89676).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG