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Invitrogen™ EAF2 Polyclonal Antibody
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Catalog No. PIPA552557
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100 μL
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PIPA552557 100 μL
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Catalog No. PIPA552557 Supplier Invitrogen™ Supplier No. PA552557
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Rabbit Polyclonal Antibody

Immunogen sequence: GFSHLDRRER VLKLGESFEK QPRCAFHTVR YDFKPASIDT SSEGYLEVGE GEQVTITLPN IEGSTPPVTV FKGSKKPYLK ECILIINHDT GECRL Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 89%.

EAF1 and EAF2 can form a complex with ELL that targets the ternary elongation complex of Pol II, stimulating the rate of elongation. In addition, EAF1 and EAF2 are important for the stability of the NuA4 histone acetyltransferase complex, which transcriptionally activates certain genes by acetylation of Histones H4 and H2A. Both EAF1 and EAF2 are ubiquitously expressed members of the EAF family that colocalize with ELL to the the Cajal bodies and nuclear speckles. EAF1 contains a C-terminal region rich in aspartic acid, glutamic acid and serine residues. EAF2 is an androgen-response gene and can act as a potent apoptosis inducer.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EAF2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Eaf2
Gene Accession No. Q96CJ1
Gene Alias AW048865; BM040; BM-040; Eaf2; Ehrlich S-II transcriptional activator factor; ELL associated factor 2; ELL-associated factor 2; Festa; FESTA-L; FESTA-S; testosterone regulated apoptosis inducer and tumor suppressor; testosterone-regulated apoptosis inducer and tumor suppressor protein; Traits; U19
Gene Symbols Eaf2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human EAF2. Recombinant protein control fragment (Product #RP-89676).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55840
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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