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Invitrogen™ EAF2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA577141

Catalog No. PIPA577141


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Description

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

EAF1 and EAF2 can form a complex with ELL that targets the ternary elongation complex of Pol II, stimulating the rate of elongation. In addition, EAF1 and EAF2 are important for the stability of the NuA4 histone acetyltransferase complex, which transcriptionally activates certain genes by acetylation of Histones H4 and H2A. Both EAF1 and EAF2 are ubiquitously expressed members of the EAF family that colocalize with ELL to the the Cajal bodies and nuclear speckles. EAF1 contains a C-terminal region rich in aspartic acid, glutamic acid and serine residues. EAF2 is an androgen-response gene and can act as a potent apoptosis inducer.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

EAF2
Polyclonal
Unconjugated
Eaf2
AW048865; BM040; BM-040; Eaf2; Ehrlich S-II transcriptional activator factor; ELL associated factor 2; ELL-associated factor 2; Festa; FESTA-L; FESTA-S; testosterone regulated apoptosis inducer and tumor suppressor; testosterone-regulated apoptosis inducer and tumor suppressor protein; Traits; U19
Rabbit
Antigen affinity chromatography
RUO
106389, 266787, 55840
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Q811X5, Q91ZD6, Q96CJ1
Eaf2
Recombinant full length Human EAF2.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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