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EAF2 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501562751
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50-156-2751 10 μL
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Catalog No. 50-156-2751 Supplier Bethyl Laboratories, Inc Supplier No. A302503AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

EAF1 and EAF2 can form a complex with ELL that targets the ternary elongation complex of Pol II, stimulating the rate of elongation. In addition, EAF1 and EAF2 are important for the stability of the NuA4 histone acetyltransferase complex, which transcriptionally activates certain genes by acetylation of Histones H4 and H2A. Both EAF1 and EAF2 are ubiquitously expressed members of the EAF family that colocalize with ELL to the Cajal bodies and nuclear speckles. EAF1 contains a C-terminal region rich in aspartic acid, glutamic acid and serine residues. EAF2 is an androgen-response gene and can act as a potent apoptosis inducer.

Specifications

Antigen EAF2
Applications Immunohistochemistry, Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene EAF2
Gene Accession No. Q96CJ1
Gene Alias BM040, testosterone-regulated apoptosis inducer and tumor suppressor protein, TRAITS, U19
Gene Symbols EAF2
Host Species Rabbit
Immunogen Between 210 and 260
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55840
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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