EAF2 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A302502A

Catalog No. 50-156-2748

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

EAF1 and EAF2 can form a complex with ELL that targets the ternary elongation complex of Pol II, stimulating the rate of elongation. In addition, EAF1 and EAF2 are important for the stability of the NuA4 histone acetyltransferase complex, which transcriptionally activates certain genes by acetylation of Histones H4 and H2A. Both EAF1 and EAF2 are ubiquitously expressed members of the EAF family that colocalize with ELL to the Cajal bodies and nuclear speckles. EAF1 contains a C-terminal region rich in aspartic acid, glutamic acid and serine residues. EAF2 is an androgen-response gene and can act as a potent apoptosis inducer.

Specifications

• Antigen: EAF2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EAF2
• Gene Alias: BM040, testosterone-regulated apoptosis inducer and tumor suppressor protein, TRAITS, U19
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55840
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunohistochemistry, Immunoprecipitation
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: Q96CJ1
• Gene Symbols: EAF2
• Immunogen: Between 150 and 200
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG